Fig. 5
From: The chromatin reader Dido3 is a regulator of the gene network that controls B cell differentiation
Analysis of the Igh locus in Dido1∆E16 pre-B cells reveals defects in gene rearrangement. A. Relative abundance of Ighv regions in the transcriptome of Dido1∆E16 pre-B cells, presented as log fold change (logFC) compared to WT levels (green dots represent significantly overexpressed regions, *, p < 0.05). The bottom section shows chromosome coordinates, while the top indicates the main regions (proximal, intermediate, distal) where distinct V families are mapped. B. Integrative Genomics Viewer (IGV; http://www.broadinstitute.org) plot displaying RNA-seq data that illustrates transcription from the DNA region between D and J regions; positions of J fragments and the more distal D fragment (D4) are represented. C. IGV plot with RNA-seq data showing transcription of the Igg2b gene in Dido1∆E16 pre-B samples