Fig. 1
From: The chromatin reader Dido3 is a regulator of the gene network that controls B cell differentiation
Altered hematopoietic cell populations in Dido1∆E16 mice indicate impaired B cell development compared to WT. A. Quantification of total (WT n = 9, Dido1∆E16 n = 9), lin⁻, LSK and CLP cells (WT n = 6, Dido1∆E16 n = 6) per single femur (t-test ** p < 0.01, * p < 0.05). Bars, mean ± SD. B. Numbers of EYFP+B220.+ cells per femur in WT compared to Dido1∆E16 mice (n = 14; **** p < 0.0001). C. Total bone marrow B precursors and mature recirculating B cells isolated from a single femur. Prepro-B (n = 6); pro-B, pre-B (WT n = 13, Dido1∆E16 n = 11); immature and mature B cells (WT n = 14, Dido1∆E16 n = 13). B, C. Means ± SD are shown, t-test **** p < 0.0001