Fig. 5

Displays the quantity and intensity of cell communication between the newly diagnosed and neoadjuvant therapy groups. (A) The network graph illustrates the variation in the number of interactions between cell types in the newly diagnosed and neoadjuvant therapy groups. The red line indicates the newly diagnosed group, while the blue line represents the neoadjuvant therapy group. The thickness of the lines represents changes in the number of interactions between cell types, with thicker lines indicating a greater number of interactions between the two cell types. (B) The network graph depicts the change in interaction intensity between cell types in the newly diagnosed and neoadjuvant therapy groups. The red line indicates the newly diagnosed group, while the blue line represents the neoadjuvant therapy group. The thickness of the lines reflects the strength of the interaction, with thicker lines indicating a stronger interaction between the two cell types. (C)The heatmap portrays the overall signaling patterns for the newly diagnosed and neoadjuvant therapy groups