Fig. 7

S protein exposure shows the influences of retinal development at the molecular levels. A The  KEGG pathway signaling interaction network of the DEGs in 90-day hEROs after S protein exposure, compared to control groups. B The KEGG pathway signaling interaction network of the DEGs in 280-day hEROs after S protein exposure, compared to control groups. C Volcano plot shows the DEGs of S protein exposure in hEROs at day 90, compared to control groups. D Volcano plot shows the DEGs of S protein exposure in hEROs at day 280, compared to control groups. E, F The relative mRNA expression level of HK2, LDHA, MYD88, and TLR4 in 90-day hEROs  after S protein exposure, compared to control groups. G, H The relative mRNA expression level of COL1A1, COL6A3, ID3, and TGFβ1 in 280-day hEROs  after S protein exposure, compared to control groups. Data are presented as means ± SD. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001