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Fig. 3 | Cell & Bioscience

Fig. 3

From: The influence of SARS-CoV-2 spike protein exposure on retinal development in the human retinal organoids

Fig. 3

The influence of the SARS-CoV-2 S protein exposure on the development of hEROs. A Schematic of S protein treatment of hEROs at different points. B The relative mRNA levels of ACE2 and TMP in hEROs at day 90 after S protein exposure, compared to control groups . C The relative mRNA levels of ACE2 and TMP in hEROs at day 280 after S protein exposure, compared to control groups . D Representative images of the expression of RECV+/ACE2+ cells and CRX+/ACE2+ cells in hEROs at days 90 and 280 after S protein exposure. E The ratio of CRX-positive cells/ area (μm2) and the average fluorescence intensity of RECV- positive cells in 90-day hEROs after S protein exposure, compared to control groups . F The ratio of CRX-positive cells/ area (μm2) and the average fluorescence intensity of RECV- positive cells in 280-day hEROs after S protein exposure, compared to control groups. Data are presented as means ± SD. Scale bar, 50 μm

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Cell & Bioscience

ISSN: 2045-3701

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