Fig. 3

Effects of clusterin deficiency on DDC diet-induced liver injury. (A, B) Representative real-time RT-PCR (A) and western blot (B) analyses of type I collagen and αSMA expression in WT and clusterin-KO mice fed a DDC diet for 20 days. *p < 0.05, **p < 0.01. (C, D) ELISAs of ALT (C) and AST (D) levels in serum of WT and clusterin-KO mice fed a DDC diet for 10 and 20 days. (E, F) ELISAs of IL1β (E) and IL18 (F) levels in serum of WT and clusterin-KO mice fed a DDC diet for 10 and 20 days. *p < 0.05, **p < 0.01, ***p < 0.001