Fig. 2

Clusterin deficiency promotes fibrosis upon DDC diet-induced liver injury. (A, B) Representative images of hematoxylin and eosin (A) and Sirius red (B) staining in WT and clusterin-KO mice fed a DDC diet (n = 4). **p < 0.01, ***p < 0.001. (C, D) Immunohistochemical analysis of collagen (C) and αSMA (D) expression in WT and clusterin-KO mice fed a DDC diet. Data in the bar graph are means ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001. Scale bars indicate 100 μm