Fig. 1

Overall structural of Tp-serpin and Ts-serpin. (A) Ribbon model of the Tp-serpin. Sheets A-C are shown in light pink, light purple and light green. RCL (in red), which is in the structure there was no electron density at the corresponding position; The helical are in light yellow; The flexible regions are in turquoise. The Breach and the shutter area are highlighted in dotted elliptical boxes. (B) Structure conservation of Tp-serpin. (C) Comparsion of structure of Tp-serpin in golden with conserpin (PDB:5CNX) [18] in cyan. (D) Ribbon model of the Ts-serpin. Sheets A-C are shown in mauve, purple and green. RCL (in red), which is in the structure there was no electron density at the corresponding position; The helical are in yellow; The flexible regions are in livid gray. The Breach and the shutter area are highlighted in dotted elliptical boxes. (E) Structure conservation of Ts-serpin. (F) Comparsion of structure of Ts-serpin in green with Human SerpinB3 (PDB:4ZK0) [19] in pink. (G) Alignment of RCL sequences of Ts-serpin and Tp-serpin with other serpins