Fig. 4
From: Shared and distinct peripheral blood immune cell landscape in MCTD, SLE, and pSS
Single-cell transcriptional landscape of MCTD, SLE, and pSS. A Experimental design and workflow of the study. B UMAP embedding of the entire dataset colored by generated clusters, labelled by cell type annotation and split by each AD as well as HCs. C Box plot showing the fraction of cell types in MCTD, SLE, and pSS. D Percentages of specific immune cell subtypes in total PBMCs from each individual. p values were calculated using the Mann–Whitney U test for comparisons between HCs and disease groups. *p < 0.05, **p < 0.01, ***p < 0.001. E Venn diagram of shared and distinct changes in cell proportions among MCTD, SLE, and pSS