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Fig. 2 | Cell & Bioscience

Fig. 2

From: Whole-genome bisulfite sequencing of cell-free DNA unveils age-dependent and ALS-associated methylation alterations

Fig. 2

Identification of age-related methylation features in cfDNA. (A) Bar graph showing average genome-wide mCG levels in young and middle-aged groups. No significant difference of methylation levels was observed between groups. (B) Identification of DML between the two groups. (C) Heatmap visualization of the methylation profiles of DMLs identified between the two groups. (D) Genomic annotation of the identified DMLs to their percentage of each genomic feature. (E) KEGG analysis for DML-associated genes to examine their biological significance

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