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Fig. 3 | Cell & Bioscience

Fig. 3

From: Transcriptomics, lipidomics, and single-nucleus RNA sequencing integration: exploring sphingolipids in MASH-HCC progression

Fig. 3

S1P and sphingosine levels in the serum and liver during MASH-HCC disease progression in DIAMOND mice. Serum and liver tissues were processed for sphingolipid analysis using LC-MS/MS. (A) S1P-d18-1, S1P-d18-0, Sph-d18-1, and Sph-d18-0 levels in the serum. (B) S1P, S1P-d18-0, Sph-d18-1, and Sph-d18-0 levels in the liver. Data are expressed as the mean ± SEM. Statistical significance relative to the corresponding CDNW group: *p < 0.05, **p < 0.01, ***p < 0.001. Statistical significance relative to CDNW-6 M or WDSW-6 M group: ##p < 0.01, ###p < 0.001 (n = 10–15)

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Cell & Bioscience

ISSN: 2045-3701

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