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Table 1 SNPs of Potassium Channels Associated with Depression

From: Potassium channels in depression: emerging roles and potential targets

SNP

Gene

Properties

References

rs6686529

KCNK2

The occurrence rate of homozygotes is significantly higher in the patient group than in the control group

[40] [41]

rs7549184

rs10779646

rs12136349

KCNK2

Variants in KCNK2 are associated with treatment responses

[42]

rs2841616

rs2841608

rs3859014

HCN4

Expression of the HCN4 gene in brain regions is associated with emotions and depression

[43]

rs12905212

rs79878474

KCNC1

The potassium channels KV3 and Kir-6.2 are closely associated with depression in children and adolescents

[44]

rs9394578

KCNK5

Genes are significantly enriched in severe depression

[45]

rs2815095