Table 1 Comprehensive literature search strategy for STGD therapies and diagnostics
From: The ABCs of Stargardt disease: the latest advances in precision medicine
Category | Search Focus | Keywords and Topics | Number of Citations |
|---|---|---|---|
Clinical Interventions and Therapies | Drug therapies | - Drug therapies STGD | 98 (17) |
Surgical interventions | - Surgical interventions STGD | 32 (6) | |
ABCA4 gene therapy | - ABCA4 gene therapy | 126 (15) | |
Retinal gene replacement | - Retinal gene replacement | 880 (11) | |
Stem cell therapy for Stargardt disease | - Stem cell therapy STGD | 65 (32) | |
Pharmacological interventions for macular degeneration | - Pharmacological interventions for macular degeneration | 1,317 (5) | |
Genetic and Molecular Research | Underlying genetic mutations | - Underlying genetic mutations STGD | 44 (8) |
Molecular pathways | - Molecular pathways STGD | 24 (3) | |
Gene therapies | - Gene therapies STGD | 137 (14) | |
Molecular mechanisms of retinal degeneration | - Molecular mechanisms of retinal degeneration | 1,914 (7) | |
Molecular pathogenesis of Stargardt disease | - Molecular pathogenesis of STGD | 243 (19) | |
Genetic variants in ABCA4 | - Genetic variants in ABCA4 | 331 (21) | |
Early STGD Diagnosis | Early diagnosis | - Early STGD diagnosis | 134 (9) |
- Early onset macular degeneration | 518 (6) | ||
- Ophthalmological biomarkers for early diagnosis STGD | 3 (2) | ||
- Early stage vision loss diagnosis | 710 (17) | ||
- STGD screening | 428 (4) | ||
- Vision loss in childhood diagnosis | 713 (3) |