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Fig. 7 | Cell & Bioscience

Fig. 7

From: Protein arginine methyltransferase 1 regulates mouse enteroendocrine cell development and homeostasis

Fig. 7

A proposed model for the role of PRMT1 in small intestinal enteroendocrine cell development. PRMT1 suppresses enteroendocrine lineage development, most likely via inhibition of Neurog3 expression through yet unknown mechanism. This may in turn inhibit the formation of Neurog3-postive progenitor cells and/or their proliferation, leading to fewer progenitor cells to differentiate into EECs. Neurogenin 3: Neurog3. EEC: Enteroendocrine cells

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Cell & Bioscience

ISSN: 2045-3701

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