Fig. 5
From: RNA editing enzymes: structure, biological functions and applications
The RNA editing enzyme ADAR1 plays a crucial role in innate immunity. Double-stranded RNA (dsRNA), whether endogenous or exogenous, can bind to cytoplasmic RNA receptors and trigger an innate immune response. The ADAR1 catalyzed A-to-I RNA editing can suppress these immune responses by disrupting RNA structure