Fig. 5

The changes of ROS/NLRP3/NF-κB signaling pathway in COPD rats. Western blot of ROS/NLRP3/NF-κB signaling pathway in lung tissue in COPD rats (A), Quantification of ROS/NLRP3/NF-κB signaling pathway in COPD rats (B). The expression levels of NLRP3 and p-NF-κBp65 in lung tissue in COPD rats by immunohistochemistry (× 200) (C). Quantification of NLRP3 (D) and p-NF-κBp65 (D) in lung tissue in COPD rats. (n = 3). All data were presented as mean ± SD. Compared with control rats: ##P < 0.01