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Fig. 5 | Cell & Bioscience

Fig. 5

From: Photobiomodulation improves the synapses and cognitive function and ameliorates epileptic seizure by inhibiting downregulation of Nlgn3

Fig. 5

tPBM reduced neuronal apoptosis in the mouse hippocampus after PI-induced excitotoxicity. A Representative images of FJB-stained brain coronal sections at 3 and 7 days after PI-induced SE. Treatment with 825 nm tPBM protected the CA1, CA3 and hilus cells of the hippocampus at 4 h after PI injection. Higher magnification views of each hippocampal region enclosed by the black boxes. The scale bars indicate 100 and 50 μm. B–D Quantitative analyses of the apoptotic neurons in hippocampal CA1, CA3, and hilus in the PI and PI + tPBM groups. CA1, cornu ammonis1; CA3, cornu ammonis 3. Data are expressed as the mean ± SEM; ***p < 0.001, ****p < 0.0001 relative to each PI group (Student’s t-test)

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Cell & Bioscience

ISSN: 2045-3701

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