Fig. 3
From: Metabolomics of blood reveals age-dependent pathways in Parkinson’s Disease

Pathway analysis. The box plots of 8 significant metabolomic parameters validated in OPLS reveal a difference of the concentration between PD and HC subjects (A). An enrichment analysis verifies that the selected parameters can be associated with the biosynthesis of unsaturated fatty acids, the tryptophan metabolism and the glycine, serine and threonine metabolism (B). We verified that the metabolites composing the first and the third pathway are correlated with age only in HG and PD subjects, respectively