Fig. 3
From: Role of FoxO transcription factors in aging and age-related metabolic and neurodegenerative diseases
Diverse functions of FoxO. Major FoxO functions are listed here to demonstrate the involvement of FoxO proteins in a variety of cellular processes. These include glucose metabolism, lipid metabolism, oxidative stress resistance, cell cycle arrest, DNA damage repair, energy homeostasis, autophagy, and apoptosis. Select transcriptional targets of FoxO proteins within each pathway are shown