Fig. 2
From: Mechanism of transcription-coupled DNA modification recognition
a Elongation of RNA polymerase II may encounter different types of DNA modifications. b These include bulky, DNA-distorting lesions (e.g. UV-induced cis-syn CPD, oxidative damage CydA), small but mutagenic DNA damage (e.g. 8-oxo-guanine), and enzyme-catalyzed endogenous DNA modifications (e.g. 5caC)