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Table 5 Univariate and multivariate analyses of various prognostic variables for overall survival in cohort 2

From: Overexpression of MACC1 and Its significance in human Breast Cancer Progression

 

Univariate analysis

Multivariate

 

P

Hazard ratio (95% CI)

P

Hazard ratio (95% CI)

Age

    

 ≤45

0.808

1.061 (0.657-1.713)

  

 >45

    

Tumor size (cm)

    

 ≤2

<0.001

3.449 (2.131-5.584)

<0.001

2.834(1.741-4.612)

 >2

Lymph node status

    

 Negative

<0.001

3.657 (1.960-6.823)

0.001

2.936(1.540-5.597)

 Positive

ER

    

 Positive

0.793

0.938 (0.583-1.509)

  

 Negative

PR

    

 Positive

0.036

0.603 (0.375-0.968)

0.002

0.465 (0.286-0.757)

 Negative

ErbB-2

    

 Positive

0.886

0.937 (0.383-2.292)

  

 Negative

MACC1 expression

    

 Positive

<0.001

4.564 (2.392-8.709)

0.001

3.190 (1.651-6.163)

 Negative