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Table 1 Clinicopathologic characteristics of patient samples in Cohorts 1 and 2

From: Overexpression of MACC1 and Its significance in human Breast Cancer Progression

Characteristic

Cohort 1

Cohort 2

 

NO.

%

NO.

%

Total

245

185

Age

 

 ≤45

95

38.8

78

42.2

 >45

150

61.2

107

57.8

Menopausal status

 

 Premenopausal

116

53.2

  

 Postmenopausal

102

46.8

  

 Unknown

27

   

Clinical stage

 

 I

81

33.1

21

11.4

 II

91

37.1

80

43.2

 III

40

16.3

59

31.9

 IV

33

13.5

25

13.5

T classification

 

 T1

110

44.9

36

19.5

 T2

107

43.7

92

49.7

 T3

18

7.3

41

22.2

 T4

10

4.1

16

8.6

N classification

 

 N0

135

55.1

70

37.8

 N1

51

20.8

78

42.2

 N2

41

16.7

30

16.2

 N3

18

7.3

7

3.8

Distant metastasis

 

 Yes

212

86.5

177

95.7

 No

33

13.5

8

4.3

Estrogen receptor

 

 Positive

174

71.0

101

54.6

 Negative

71

29.0

84

45.4

 Unknown

0

 

0

 

Progesterone receptor

 

 Positive

146

66.3

110

59.5

 Negative

74

33.7

75

40.5

 Unkown

25

 

0

 

Her2

 

 Positive

43

22.3

21

21.4

 Negative

150

77.7

77

78.6

 Unknown

52

 

87

 

MACC1 expression

    

 High expression

136

55.5

111

60.0

 Low expression

109

44.5

74

40.0

Endocrine therapy

 

 tamoxifen

122

43.8

  

 No treatment

95

56.2

  

 Unknown

28